The Common Immunogenic Etiology of Chronic
Fatigue Syndrome: From Infections to Vaccines
via Adjuvants to the ASIA Syndrome.

Rosenblum H, Shoenfeld Y, Amital H.

Department of Medicine B, Sheba Medical Center, Sackler Faculty of
Medicine, Tel Aviv University, Ramat Aviv, Tel-Hashomer 52621,
Israel; Zabludowicz Center for Autoimmune Diseases, Sheba
Medical Center, Sackler Faculty of Medicine, Tel Aviv University,
Ramat Aviv, Tel-Hashomer 52621, Israel.


Abstract

Chronic fatigue syndrome (CFS) is characterized by unexplained
fatigue that lasts for at least 6 months with a constellation of other
symptoms.

Most cases start suddenly, and are usually accompanied by a
flu-like illness. It is a symptom-based diagnosis of exclusion, the
pathogenesis of which is unknown.

Studies have examined and hypothesized about the possible
biomedical and epidemiologic characteristics of the disease,
including genetic predisposition, infections, endocrine abnormalities,
and immune dysfunction and psychological and psychosocial
factors.

Recently, the AISA (autoimmune/inflammatory syndrome induced by
adjuvants) syndrome was recognized, indicating the possible
contribution of adjuvants and vaccines to the development of
autoimmunity.

Copyright © 2011 Elsevier Inc. All rights reserved.


PMID: 22054760 [PubMed - in process]

Infect Dis Clin North Am. 2011 Dec;25(4):851-63. Epub 2011 Sep 9.
http://www.ncbi.nlm.nih.gov/pubmed/22054760
PubMed

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ASIA Syndrome - See for example:

http://j.mp/tEFcmZ

' ASIA ' - Autoimmune/inflammatory syndrome induced by adjuvants.

Shoenfeld Y, Agmon-Levin N.

J Autoimmun

@